Oxygono works closely with civil society, public organizations, universities, businesses, media and other key figures and institutions to discuss, exchange and formulate views on key issues related to public policy both in Cyprus and internationally. It maintains close cooperation, among other entities, with the University of Cyprus, the Cyprus University of Technology, the Municipality of Larnaca, the Municipality of Paphos, the Municipality of Limassol, the Cyprus News Agency, the Cyprus Youth Organization, and is a member of the Cyprus Youth Council.